An Anodyne Epithem.
Take Brandy 4 ounces; Camphire half a dram; Opium 2 drams, dissolve.
It comforts the Nervous parts, by its warmth appeaseth the raging Spirits, penetrates deep, sets open the Pores, attenuates, dissipates, obtunds the dolorific Matter, and drives it off by Diaphoresis.
Thomas Fuller
Pharmacopeia Extemporanea 1710