An Icteric Plaister.
Take powered Saffron 2 drams; make a Plaister of it with Honey, which spread upon a piece of Leather, and lay it so as to cover the Region of the Liver and Navel.
It was the Experiment of an eminent Physician, for small Children affected with the Icterus, who can take little.
Thomas Fuller
Pharmacopeia Extemporanea 1710