Piony Powder compound.
Take Male Piony root, Humane Cranium, each 5 grains; native Cinnaber half a scruple; Oil of Nutmeg 1 drop; bring it to a Powder.
This Powder being fetch'd out of the triple Kingdom, Animal, Vegetable and Mineral, very notably succours Children troubled with Convulsion Fits.
Thomas Fuller
Pharmacopeia Extemporanea 1710