Decoction of Seneka.
Take of seneka rattle-snake root, one ounce; water, a pint and a half. Boil to one pint, and strain.
This decoction is recommended in the pleurisy, dropsy, rheumatism, and some obstinate disorders of the skin. The dose is two ounces, three or four times a-day, or oftener, if the stomach will bear it.
William Buchan
Domestic Medicine 2nd edition 1785