Plummer's Pill.
Take of calomel, or sweet mercury, and precipitated sulphur of antimony, each three drachms; extract of liquorice, two drachms. Rub the sulphur and mercury well together; afterwards add the extract, and, with a sufficient quantity of the mucilage of gum arabic, make them into pills.
This pill has been found a powerful, yet safe, alterative in obstinate cutaneous disorders; and has completed a cure after salivation had failed. In venereal cases it has likewise produced excellent effects. Two or three pills of an ordinary size may be taken night and morning, the patient keeping moderately warm and drinking after each dose a draught of decoction of the woods, or of sarsaparilla.
William Buchan
Domestic Medicine 2nd edition 1785